2017 – Pittsford, NY

Oct 31, 2017

The 2017 meeting was held on 1st to 3rd June 2017 in Pittsford, which is near Rochester, NY, at the Del Monte Renaissance Hotel, Pittsford, NY.

Themes for the scientific sessions on Friday 2nd June were “Fluorochromes” and “Autophagy and use of new techniques that can detect it in cancers.” There were also presentations from the University of Rochester Department of Pathology. Here is the program.

BIOLOGICAL STAIN COMMISSION

2017 ANNUAL MEETING  Friday 2nd June 2017

 PROGRAM

Morning Session      Presentations by Residents and Faculty, Department of Pathology and Laboratory Medicine at University of Rochester Medical Center

8:00—8:15 a.m.         PD-L1 expression in esophageal adenocarcinoma and squamous cells carcinoma with clinicopathologic features.  Sohaib Abu-Farsakh, Amy Lalonde, Tongtong Wu, Zhongren Zhou

8:15—8:30 a.m.         Immunohistochemistry as a surrogate for molecular subtyping of gastric adenocarcinoma.  Raul S. Gonzalez, Susan Messing, Xin Tu, Loralee A. McMahon, Christa L. Whitney-Miller.

8:30—8:45 a.m.         Age less than forty is predictive of mismatch protein loss in colorectal tubulovillous.  Sohaib Abu-Farsakh, Danielle Marino, Arthur DeCross, Qi Yang, Loralee McMahon, Jennifer J. Findeis-Hosey

8:45—9:00 a.m.         Morphological features and prognostic significance of ARID1A deficient esophageal adenocarcinomas.  Michael G. Drage, Mingkhwan Tippayawong, Agoston T. Agoston, Yifan Zheng, Raphael Bueno, Jason L. Hornick, Robert D. Odze, Amitabh Srivastava

9:00—9:15 a.m.         Expression of epithelial-mesenchymal transition markers E-Cadherin and vimentin in esophageal adenocarcinoma and squamous cell carcinoma and significant association with new proliferation markers MCM4 and MCM7.  Meenal Sharma, Zhongren David Zhou

9:15—9:30 a.m.         High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7.  Aaron R. Huber,.Dongfeng Tan,.Jun Sun,,David Dean,,Tongtong Wu and Zhongren Zhou

9:30—9:45 a.m.         Selective loss of PTEN expression in germinal center-derived B cell lymphomas lacking surface immunoglobulin.  Hani Katerji, W. Richard Burack, Andrew G. Evans

9:45—10:00 a.m.       Continuous versus discontinuous tumor involvement: A dilemma in prostate biopsy quantitation.  Caroline Bsirini, Alexandra M. Danakas, Hiroshi Miyamoto

10:00—10:30 a.m.    Break

10:30—11:00 a.m.    Preliminary outcome data comparing oncotype diagnosis and morphology/immunohistochemistry “Old school versus new school”. Bradley M. Turner, Armen Soukiazian, Ping Tang, David Hicks

11:00—11:30 a.m.    HER2 expression in clinical breast cancer samples: a novel detection methodology for HER2 protein quantitation using fluorescent nanoparticles. David G. Hicks, Hideki Goda, Haiyan Zhai, Hisatake Okada, Loralee McMahon, Nicole Sullivan, Ping Tang, Yasushi Nakano

11:30—12:00 noon  BSC Annual Business meeting. (Minutes were emailed to members of the BSC, including those not present at the AGM, about 2 weeks later. Business included election to the Board of Trustees, Committee reports, and new collaborations: educational with the Society of Dyers and Colourists, and research on dye quality evaluation with the University of Leeds, UK. Representatives of Millipore-Sigma, a major vendor of Certified Stains, distributed interesting promotional and educational materials in the fields of Special Stains and Tissue Diagnostics.) 

12:00—1:30 p.m.      Lunch

Afternoon Session      Fluorochromes, and Autophagy in Cancer

 1:30—2:00 p.m.         Are fluorescent probes purer, and more “rational,” than traditional biological stains? Richard W Horobin [Chemical Biology, University of Glasgow, Scotland, UK] and Lacey McNally [Pharmacology & Toxicology, Wake Forest University, USA]

2:00—2:30 p.m.         Fluorescent Dyes for Labelling in Chemical Biology. Hans Schmitthenner. School of Chemistry and Material Science, Rochester Institute of Technology, Rochester, NY

2:30—3:00 p.m.         Introduction to Autophagy. Bill Grizzle, Department of Pathology, University of Alabama, Birmingham, AL

3.00—3.30 p.m.         Coffee break

3.30—4:00 p.m.         Role of Autophagy in Colon Cancer. Abhilash Samykutty, Department of Cancer Biology at Wake Forest Comprehensive Cancer Center. Winston-Salem, NC

4:00—4:30 p.m.         Epigenetic regulation of Beclin 1 network in cancer.   Anna Woloszynska-Read, Department of Pharmacology and Therapeutics Roswell Park Cancer Institute, Buffalo, NY

4:30—5:00 p.m.         Cancer recurrence and chemoresistance: the importance of autophagy.  Lacey McNally, Department of Cancer Biology at Wake Forest Comprehensive Cancer Center. Winston-Salem, NC

7:00—9:30 p.m.        Reception and dinner.  (This was an enjoyable social occasion, at which members who attend regularly met with newcomers, including invited speakers and local presenters.)